Chemical biology of natural products
Isolation and structural elucidation of novel natural products from termite-associated microbes
Structural elucidation and discovery biological activities of natural compounds from Korean wild mushroom and fungi
학력
2007-2011 (박사) 성균관대학교 약학대학
2005-2007 (석사) 성균관대학교 약학대학
2001-2005 (학사) 성균관대학교 약학대학
약력/경력
2011-2012 성균관대학교 (Postdoctoral researcher)
2012-2012 Harvard University (Postdoctoral Research Fellow)
2012-2014 Harvard Medical School (Postdoctoral Research Fellow)
2014- 현재 대한약학회 (Associate Editor)
2014- 현재 고려인삼학회 (Associate Editor)
학술지 논문
(2023)
Performance-enhanced eco-friendly triboelectric nanogenerator via wettability manipulation of lignin.
ECOMAT.
5,
.
(2023)
Inonotus obliquus upregulates muscle regeneration and augments function through muscle oxidative metabolism.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES.
19,
15
(2023)
Development of a screening platform to discover natural products active against SARS-CoV-2 infection using lung organoid models.
BIOMATERIALS RESEARCH.
27,
1
(2022)
Ultra-intimate hydrogel hybrid skin patch with asymmetric elastomeric spatula-like cylinders.
CHEMICAL ENGINEERING JOURNAL.
444,
(2022)
Recent advances in pain management based on nanoparticle technologies.
JOURNAL OF NANOBIOTECHNOLOGY.
20,
1
(2022)
Biocompatible and mechanically-reinforced tribopositive nanofiber mat for wearable and antifungal human kinetic-energy harvester based on wood-derived natural product.
NANO ENERGY.
96,
(2022)
Termite Nest Associated Bacillus siamensis YC-9 Mediated Biocontrol of Fusarium oxysporum f. sp. cucumerinum.
FRONTIERS IN MICROBIOLOGY.
13,
(2022)
Identification of anti-adipogenic withanolides from the roots of Indian ginseng (Withania somnifera).
JOURNAL OF GINSENG RESEARCH.
46,
3
(2022)
A New Labdane-Type Diterpene, 6-O-Acetyl-(12R)-epiblumdane, from Stevia rebaudiana Leaves with Insulin Secretion Effect.
BIOMEDICINES.
10,
4
(2022)
Nano-liposomal zein hydrolysate for improved apoptotic activity and therapeutic index in lung cancer treatment.
DRUG DELIVERY.
29,
1
(2022)
Cyclohumulanoid Sesquiterpenes Induced by the Noncompetitive Coculture of Phellinus orientoasiaticus and Xylodon flaviporus.
JOURNAL OF NATURAL PRODUCTS.
85,
3
(2022)
Non-peptide secondary metabolites from poisonous mushrooms: overview of chemistry, bioactivity, and biosynthesis.
NATURAL PRODUCT REPORTS.
39,
3
(2022)
Antioxidant and Cytotoxic Activities of Kudzu Roots and Soy Molasses against Pediatric Tumors and Phytochemical Analysis of Isoflavones Using HPLC-DAD-ESI-HRMS.
PLANTS-BASEL.
11,
6
(2022)
Identification of Antibacterial Sterols from Korean Wild Mushroom Daedaleopsis confragosa via Bioactivity- and LC-MS/MS Profile-Guided Fractionation.
MOLECULES.
27,
6
(2022)
Structural Characterization of Withanolide Glycosides from the Roots of Withania somnifera and Their Potential Biological Activities.
PLANTS-BASEL.
11,
6
(2022)
Enhanced biocompatibility and multidirectional wet adhesion of insect-like synergistic wrinkled pillars with microcavities.
CHEMICAL ENGINEERING JOURNAL.
429,
(2022)
First Chemical Investigation of Korean Wild Mushroom, Amanita hemibapha subsp. javanica and the Identification of Anti-Helicobacter pylori Compounds.
PHARMACEUTICALS.
15,
2
(2022)
Improvement of Damage in Human Dermal Fibroblasts by 3,5,7-Trimethoxyflavone from Black Ginger (Kaempferia parviflora).
ANTIOXIDANTS.
11,
2
(2022)
New phenalenone derivatives from the Hawaiian volcanic soil-associated fungus Penicillium herquei FT729 and their inhibitory effects on indoleamine 2,3-dioxygenase 1 (IDO1).
ARCHIVES OF PHARMACAL RESEARCH.
45,
2
(2022)
Terminalin from African Mango (Irvingia gabonensis) Stimulates Glucose Uptake through Inhibition of Protein Tyrosine Phosphatases.
BIOMOLECULES.
12,
2
단행본
(2019)
천연물의약품.
동명사.
공동
(2016)
천연물 의약품.
동명사.
공동
특허/프로그램
신규 화합물 및 이를 유효성분으로 함유하는 암의 예방 또는 치료용 조성물.
10-2019-0132722.
20211201.
대한민국
NOVEL COMPOUNDS AND METHOD OF PREVENTING OR TREATING CANCER USING THE SAME.
16/879,030.
20211119.
미국
사이클릭 트리펩타이드, 이의 제조 방법, 및 이를 포함하는 미백용 조성물.
10-2019-0109976.
20200323.
대한민국
Novel compound promoting osteoblast differentiation and inhibiting adipocyte differentiation, preparation method thereof and application thereof.
US 16/300086.
20191203.
미국
야관문 추출물의 분획물을 포함하는 암의 예방 또는 치료용 약학적 조성물.
10-2018-0004289.
20191129.
대한민국
Novel compound promoting osteoblast differentiation and inhibiting adipocyte differentiation, preparation method thereof and application thereof.
2018-560108.
20191025.
일본
말톨, 이소소이아말로사이드 I 또는 이들의 혼합물을 유효성분으로 함유하는 아토피성 피부염 예방 또는 치료용 조성물.
10-2018-0056547.
20181228.
대한민국
조골세포 분화를 촉진하며 지방세포 분화를 억제하는 신규화합물,그 제조방법 및 그 응용.
10-2017-0059133.
20180905.
대한민국
항염증 활성 조성물 및 이를 포함하는 염증 질환 예방 또는 치료용 약학적 조성물.
10-2014-0070369.
20160107.
대한민국
수상/공훈
젊은 생약학자상/산학협력대전 우수과제 수상/대한약학회, 한국생약학회, 고려인삼학회 활동
SKKU Young Fellow
학술회의논문
(2020)
A New Trichothecene Derivative and a New Amino Acid Derivative from a Toxic Mushroom, Podostroma cornu-damae.
한국생약학회 제51회 정기총회 및 학술대회.
대한민국
(2020)
Cucurbitane Triterpenoidal Saponins from the Fruits of Momordica charantia.
한국생약학회 제51회 정기총회 및 학술대회.
대한민국
(2020)
Ergostane-type Steroids from Korean Wild Mushroom Daedaleopsis confragosa and Evaluation of Their Effects on Lipid Metabolism and Adipogenesis.
한국생약학회 제51회 정기총회 및 학술대회.
대한민국
(2020)
New Illudalane-Type Sesquiterpenes from Russula japonica.
한국생약학회 제51회 정기총회 및 학술대회.
대한민국
(2020)
Withanolides and withanosides from the Roots of Indian Ginseng (Withania somnifera).
한국생약학회 제51회 정기총회 및 학술대회.
대한민국
(2020)
Microbial Natural Products: A Promising Source for Drug Discovery.
2020년 한국미생물.생명공학회 국제학술대회 및 정기학술대회.
대한민국
(2020)
Discovery of New Aliphatic and Related Natural Products and Their Biological Evaluations.
한국질량분석학회 2020년 여름정기학술대회.
대한민국
(2020)
Discovery on New Secondary Metabolites (Natural Products) and Their Biological Evaluation.
2020 International Symposium and Annual Meeting of the KSABC.
대한민국
(2019)
Anti-inflammatory constituents from fruits of Hippophae rhamnoides.
The 50th Annual Meeting and Symposium of the Korean Society of Pharmacognosy.
대한민국
(2019)
New sesquiterpenes from the edible fungus Phellinus baumii.
The 50th Annual Meeting and Symposium of the Korean Society of Pharmacognosy.
대한민국
(2019)
Sanjoins A-D, the first diarylundecanoids with an unprecedented carbon skeleton from the seeds of Zizyphus jujuba var. spinosa (Bunge) Hu ex H.F. Chow..
The 50th Annual Meeting and Symposium of the Korean Society of Pharmacognosy.
대한민국
(2019)
Aviculin from Lespedeza cuneata suppresses MCF-7 human breast cancer cell proliferation through induction of apoptosis.
2019 Fall International Convention of The Pharmaceutical Society of Korea.
대한민국
(2019)
Polyacetylene, abscisic acid, and propionic acid derivatives from the florets of Carthamus tinctorius.
2019 Fall International Convention of The Pharmaceutical Society of Korea.
대한민국
(2019)
Trichothecene and tremulane sesquiterpenes from a hallucinogenic mushroom Gymnopilus junonius.
2019 Fall International Convention of The Pharmaceutical Society of Korea.
대한민국
(2019)
Discovery on new fungal secondary metabolites and their biological evaluation.
The 10th Korea-Japan Chemical Biology Symposium and 30th Meeting for New Drug Discovery.
일본
(2019)
Chemical Constituents and Bioactive Potential of Garlic (Allium sativum L.).
60th Anniversary of the The American Society of Pharmacognosy Annual Meeting.
미국
(2019)
New 1,3-Diphenyl Pentane Norlignans from Pueraria Lobata Roots.
60th Anniversary of the The American Society of Pharmacognosy Annual Meeting.
미국
(2019)
New Chemical Constituents from Omani Woodfordia uniflora and their Biological Properties.
60th Anniversary of the The American Society of Pharmacognosy Annual Meeting.
미국
(2019)
New Megastigmanes from Opuntia humifusa Cladodes.
60th Anniversary of the The American Society of Pharmacognosy Annual Meeting.
미국
(2019)
New Phenylpropanoid Derivatives Conjugated with Aliphatic Alcohol from the Roots of Indian Ginseng (Withania somnifera).
60th Anniversary of the The American Society of Pharmacognosy Annual Meeting.
대한민국
